Lipid Flippase Subunit Cdc50 Mediates Drug Resistance and Virulence in Cryptococcus neoformans

Cryptococcus neoformans is a human fungal pathogen and a major cause of fungal meningitis in immunocompromised individuals. Treatment options for cryptococcosis are limited. Of the two major antifungal drug classes, azoles are active against C. neoformans but exert a fungistatic effect, necessitatin...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Huang, Wei, Liao, Guojian, Baker, Gregory M., Wang, Yina, Lau, Richard, Paderu, Padmaja, Perlin, David S., Xue, Chaoyang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959666/
https://ncbi.nlm.nih.gov/pubmed/27165800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00478-16
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