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More than flipping the lid: Cdc50 contributes to echinocandin resistance by regulating calcium homeostasis in Cryptococcus neoformans

Echinocandins are the newest fungicidal drug class approved for clinical use against common invasive mycoses. Yet, they are ineffective against cryptococcosis, predominantly caused by Cryptococcus neoformans. The underlying mechanisms of innate echinocandin resistance in C. neoformans remain unclear...

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Detalhes bibliográficos
Publicado no:Microb Cell
Main Authors: Cao, Chengjun, Xue, Chaoyang
Formato: Artigo
Idioma:Inglês
Publicado em: Shared Science Publishers OG 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7136755/
https://ncbi.nlm.nih.gov/pubmed/32274390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/mic2020.04.714
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