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Cryptococcus neoformans Resistance to Echinocandins: (1,3)β-Glucan Synthase Activity Is Sensitive to Echinocandins

(1,3)β-d-Glucan synthase (EC 2.4.1.34. UDP-glucose: 1,3-β-d-glucan 3-β-glucosyltransferase) uses UDP-glucose as substrate and catalyzes the polymerization of glucose ([1,3]-β-linkages) to form the major carbohydrate component of the fungal cell wall. We have optimized in vitro assay conditions for (...

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Detalles Bibliográficos
Main Authors: Maligie, Marybeth A., Selitrennikoff, Claude P.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168702/
https://ncbi.nlm.nih.gov/pubmed/15980360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.7.2851-2856.2005
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