More than flipping the lid: Cdc50 contributes to echinocandin resistance by regulating calcium homeostasis in Cryptococcus neoformans

Echinocandins are the newest fungicidal drug class approved for clinical use against common invasive mycoses. Yet, they are ineffective against cryptococcosis, predominantly caused by Cryptococcus neoformans. The underlying mechanisms of innate echinocandin resistance in C. neoformans remain unclear...

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Publicado en:Microb Cell
Autores principales: Cao, Chengjun, Xue, Chaoyang
Formato: Artigo
Lenguaje:Inglês
Publicado: Shared Science Publishers OG 2020
Materias:
Microreview
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7136755/
https://ncbi.nlm.nih.gov/pubmed/32274390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/mic2020.04.714
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