Efficacy of Oral Cochleate-Amphotericin B in a Mouse Model of Systemic Candidiasis

Amphotericin B (AMB) remains the principal therapeutic choice for deep mycoses. However, its application is limited by toxicity and a route of administration requiring slow intravenous injection. An oral formulation of this drug is desirable to treat acute infections and provide prophylactic therapy...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Santangelo, Rosaria, Paderu, Padmaja, Delmas, Guillaume, Chen, Zi-Wei, Mannino, Raphael, Zarif, Leila, Perlin, David S.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Experimental Therapeutics
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90069/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10952579/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.9.2356-2360.2000
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