Efficacy of Orally Delivered Cochleates Containing Amphotericin B in a Murine Model of Aspergillosis

Cochleates containing amphotericin B (CAMB) were administered orally at doses ranging from 0 to 40 mg/kg of body weight/day for 14 days in a murine model of systemic aspergillosis. The administration of oral doses of CAMB (20 and 40 mg/kg/day) resulted in a survival rate of 70% and a reduction in co...

Fuld beskrivelse

Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Delmas, G., Park, S., Chen, Z. W., Tan, F., Kashiwazaki, R., Zarif, L., Perlin, D. S.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2002
Fag:	Experimental Therapeutics
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127382/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12121962/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.8.2704-2707.2002
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!