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Antifungal Activity of Amphotericin B Cochleates against Candida albicans Infection in a Mouse Model

Cochleates are lipid-based supramolecular assemblies composed of natural products, negatively charged phospholipid, and a divalent cation. Cochleates can encapsulate amphotericin B (AmB), an important antifungal drug. AmB cochleates (CAMB) have a unique shape and the ability to target AmB to fungi....

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Detalhes bibliográficos
Main Authors: Zarif, Leila, Graybill, John R., Perlin, David, Najvar, Laura, Bocanegra, Rosie, Mannino, Raphael J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC89898/
https://ncbi.nlm.nih.gov/pubmed/10817694
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