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Caspofungin Uptake Is Mediated by a High-Affinity Transporter in Candida albicans

The uptake of the echinocandin drug caspofungin acetate in Candida albicans was evaluated at drug levels at or near the MIC for the organism. Maximal uptake was achieved in 10 min and was energy independent. A saturable transport system, consistent with a facilitated-diffusion carrier, was observed...

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書目詳細資料
Main Authors: Paderu, Padmaja, Park, Steven, Perlin, David S.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2004
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC521903/
https://ncbi.nlm.nih.gov/pubmed/15388444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.10.3845-3849.2004
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