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Caspofungin Uptake Is Mediated by a High-Affinity Transporter in Candida albicans
The uptake of the echinocandin drug caspofungin acetate in Candida albicans was evaluated at drug levels at or near the MIC for the organism. Maximal uptake was achieved in 10 min and was energy independent. A saturable transport system, consistent with a facilitated-diffusion carrier, was observed...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2004
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC521903/ https://ncbi.nlm.nih.gov/pubmed/15388444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.10.3845-3849.2004 |
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