Nature versus Nurture in Glioblastoma: Microenvironment and Genetics Can Both Drive Mesenchymal Transcriptional Signature

Por Orr, Brent A., Eberhart, Charles G.
Publicado em 2012

Molecular Pathways: Not a Simple Tube—The Many Functions of Blood Vessels

Por Orr, Brent A., Eberhart, Charles G.
Publicado no Clin Cancer Res (2014)

Complete clinical regression of a BRAF V600E-mutant pediatric glioblastoma multiforme after BRAF inhibitor therapy

Por Robinson, Giles W, Orr, Brent A, Gajjar, Amar
Publicado em 2014

Recurrent BCOR internal tandem duplication and BCOR or BCL6 expression distinguish primitive myxoid mesenchymal tumor of infancy from congenital infantile fibrosarcoma

Por Santiago, Teresa, Clay, Michael R., Allen, Sariah, Orr, Brent A.
Publicado no Mod Pathol (2017)

Neoplastic cells are a rare component in human glioblastoma microvasculature

Por Rodriguez, Fausto J., Orr, Brent A., Ligon, Keith L., Eberhart, Charles G.
Publicado em 2012

Prolonged Inhibition of Glioblastoma Xenograft Initiation and Clonogenic Growth Following In Vivo Notch Blockade

Por Chu, Qian, Orr, Brent A., Semenkow, Samantha, Bar, Eli E., Eberhart, Charles G.
Publicado em 2013

Decreased 5-Hydroxymethylcytosine Is Associated with Neural Progenitor Phenotype in Normal Brain and Shorter Survival in Malignant Glioma

Por Orr, Brent A., Haffner, Michael C., Nelson, William G., Yegnasubramanian, Srinivasan, Eberhart, Charles G.
Publicado em 2012

cMYC Expression in Infiltrating Gliomas: Associations with IDH1 Mutations, Clinicopathologic Features and Outcome

Por Odia, Yazmin, Orr, Brent A., Bell, W. Robert, Eberhart, Charles G., Rodriguez, Fausto J.
Publicado em 2013

Yes-Associated Protein 1 (YAP1) Is Widely Expressed in Human Brain Tumors and Promotes Glioblastoma Growth

Por Orr, Brent A., Bai, Haibo, Odia, Yazmin, Jain, Deepali, Anders, Robert A., Eberhart, Charles G.
Publicado em 2011

Alisertib is active as single agent in recurrent atypical teratoid rhabdoid tumors in 4 children

Por Wetmore, Cynthia, Boyett, James, Li, Shaoyu, Lin, Tong, Bendel, Anne, Gajjar, Amar, Orr, Brent A.
Publicado no Neuro Oncol (2015)

Papillary tumor of the pineal region in a 15-month-old boy

Por Li, Jessica, Recinos, Pablo F., Orr, Brent A., Burger, Peter C., Jallo, George I., Recinos, Violette Renard
Publicado no J Neurosurg Pediatr (2011)

Pharmacological WNT Inhibition Reduces Proliferation, Survival and Clonogenicity of Glioblastoma Cells

Por Kahlert, Ulf D., Suwala, Abigail K., Koch, Katharina, Natsumeda, Manabu, Orr, Brent A., Hayashi, Masanori, Maciaczyk, Jarek, Eberhart, Charles G.
Publicado no J Neuropathol Exp Neurol (2015)

Oncogenic KRAS promotes malignant brain tumors in zebrafish

Por Ju, Bensheng, Chen, Wenbiao, Orr, Brent A, Spitsbergen, Jan M, Jia, Sujuan, Eden, Christopher J, Henson, Hannah E, Taylor, Michael R
Publicado no Mol Cancer (2015)

Atypical Teratoid/Rhabdoid Tumor (ATRT) Arising from the 3rd Cranial Nerve in Infants: A Clinical-Radiological Entity?

Por Oh, Christopher C., Orr, Brent A., Bernardi, Bruno, Garré, Maria Luisa, Rossi, Andrea, Figà-Talamanca, Lorenzo, Robinson, Giles W., Patay, Zoltán
Publicado no J Neurooncol (2015)

Successive Distinct High-Grade Gliomas in L-2-hydroxyglutaric Aciduria

Por Patay, Zoltan, Orr, Brent A., Shulkin, Barry L., Hwang, Scott N., Ying, Yuan, Broniscer, Alberto, Boop, Frederick A., Ellison M.D., David W.
Publicado no J Inherit Metab Dis (2014)

Yes-Associated Protein 1 Is Activated and Functions as an Oncogene in Meningiomas

Por Baia, Gilson S., Caballero, Otavia L., Orr, Brent A., Lal, Anita, Ho, Janelle S.Y., Cowdrey, Cynthia, Tihan, Tarik, Mawrin, Christian, Riggins, Gregory J.
Publicado no Mol Cancer Res (2012)

The TORC1/2 inhibitor TAK228 sensitizes atypical teratoid rhabdoid tumors to cisplatin-induced cytotoxicity

Por Rubens, Jeffrey A, Wang, Sabrina Z, Price, Antoinette, Weingart, Melanie F, Allen, Sariah J, Orr, Brent A, Eberhart, Charles G, Raabe, Eric H
Publicado no Neuro Oncol (2017)

Molecular and Morphologic Correlates of the Alternative Lengthening of Telomeres Phenotype in High‐Grade Astrocytomas

Por Nguyen, Doreen N., Heaphy, Christopher M., de Wilde, Roeland F., Orr, Brent A., Odia, Yazmin, Eberhart, Charles G., Meeker, Alan K., Rodriguez, Fausto J.
Publicado em 2012

Gliomatosis cerebri in children shares molecular characteristics with other pediatric gliomas

Por Broniscer, Alberto, Chamdine, Omar, Hwang, Scott, Lin, Tong, Pounds, Stanley, Onar-Thomas, Arzu, Shurtleff, Sheila, Allen, Sariah, Gajjar, Amar, Northcott, Paul, Orr, Brent A.
Publicado no Acta Neuropathol (2016)

Phase I study of 5-fluorouracil in children and young adults with recurrent ependymoma

Por Wright, Karen D., Daryani, Vinay M., Turner, David C., Onar-Thomas, Arzu, Boulos, Nidal, Orr, Brent A., Gilbertson, Richard J., Stewart, Clinton F., Gajjar, Amar
Publicado no Neuro Oncol (2015)