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Prolonged Inhibition of Glioblastoma Xenograft Initiation and Clonogenic Growth Following In Vivo Notch Blockade
PURPOSE: To examine the effects of clinically relevant pharmacological Notch inhibition on glioblastoma xenografts. EXPERIMENTAL DESIGN: Murine orthotopic xenografts generated from temozolomide sensitive and resistant glioblastoma neurosphere lines were treated with the γ-secretase inhibitor MRK003....
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3686970/ https://ncbi.nlm.nih.gov/pubmed/23630166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-2119 |
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