NOTCH blockade combined with radiation therapy and temozolomide prolongs survival of orthotopic glioblastoma

Glioblastoma multiforme (GBM) is the most common malignant brain tumor in adults. The current standard of care includes surgery followed by radiotherapy (RT) and chemotherapy with temozolomide (TMZ). Treatment often fails due to the radiation resistance and intrinsic or acquired TMZ resistance of a...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Yahyanejad, Sanaz, King, Henry, Iglesias, Venus Sosa, Granton, Patrick V., Barbeau, Lydie M.O., van Hoof, Stefan J., Groot, Arjan J., Habets, Roger, Prickaerts, Jos, Chalmers, Anthony J., Eekers, Daniëlle B.P., Theys, Jan, Short, Susan C., Verhaegen, Frank, Vooijs, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173056/
https://ncbi.nlm.nih.gov/pubmed/27183910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9275
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