NOTCH blockade combined with radiation therapy and temozolomide prolongs survival of orthotopic glioblastoma

Glioblastoma multiforme (GBM) is the most common malignant brain tumor in adults. The current standard of care includes surgery followed by radiotherapy (RT) and chemotherapy with temozolomide (TMZ). Treatment often fails due to the radiation resistance and intrinsic or acquired TMZ resistance of a...

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Vydáno v:Oncotarget
Hlavní autoři: Yahyanejad, Sanaz, King, Henry, Iglesias, Venus Sosa, Granton, Patrick V., Barbeau, Lydie M.O., van Hoof, Stefan J., Groot, Arjan J., Habets, Roger, Prickaerts, Jos, Chalmers, Anthony J., Eekers, Daniëlle B.P., Theys, Jan, Short, Susan C., Verhaegen, Frank, Vooijs, Marc
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173056/
https://ncbi.nlm.nih.gov/pubmed/27183910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9275
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