Synergistic Effects of NOTCH/γ-Secretase Inhibition and Standard of Care Treatment Modalities in Non-small Cell Lung Cancer Cells

Background: Lung cancer is the leading cause of cancer death worldwide. More effective treatments are needed to increase durable responses and prolong patient survival. Standard of care treatment for patients with non-operable stage III-IV NSCLC is concurrent chemotherapy and radiation. An activated...

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Опубликовано в: :Front Oncol
Главные авторы: Sosa Iglesias, Venus, Theys, Jan, Groot, Arjan J., Barbeau, Lydie M. O., Lemmens, Alyssa, Yaromina, Ala, Losen, Mario, Houben, Ruud, Dubois, Ludwig, Vooijs, Marc
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2018
Предметы:
Oncology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6234899/
https://ncbi.nlm.nih.gov/pubmed/30464927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00460
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