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The Role of Adams in Notch Signaling

Regulated intramembrane proteolysis (RIP) is a highly conserved signaling paradigm whereby membrane-bound signaling proteins are cleaved in their transmembrane region and then released into the cytoplasm to act as signaling molecules. In most if not all cases intramembrane cleavage is preceded and r...

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Main Authors: Groot, Arjan J., Vooijs, Marc A.
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050497/
https://ncbi.nlm.nih.gov/pubmed/22399336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4614-0899-4_2
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