Clostridium to treat cancer: dream or reality?

Por Theys, Jan, Lambin, Philippe
Publicado no Ann Transl Med (2015)

Targeting Notch to overcome radiation resistance

Por Yahyanejad, Sanaz, Theys, Jan, Vooijs, Marc
Publicado no Oncotarget (2015)

Regulated Proteolysis of NOTCH2 and NOTCH3 Receptors by ADAM10 and Presenilins

Por Groot, Arjan J., Habets, Roger, Yahyanejad, Sanaz, Hodin, Caroline M., Reiss, Karina, Saftig, Paul, Theys, Jan, Vooijs, Marc
Publicado em 2014

Lysine 63-Polyubiquitination Guards against Translesion Synthesis–Induced Mutations

Por Chiu, Roland K, Brun, Jan, Ramaekers, Chantal, Theys, Jan, Weng, Lin, Lambin, Philippe, Gray, Douglas A, Wouters, Bradly G
Publicado em 2006

Diminished Carcinogen Detoxification Is a Novel Mechanism for Hypoxia-inducible Factor 1-mediated Genetic Instability

Por Schults, Marten A., Timmermans, Leen, Godschalk, Roger W., Theys, Jan, Wouters, Bradly G., van Schooten, Frederik J., Chiu, Roland K.
Publicado em 2010

E-Cadherin loss associated with EMT promotes radioresistance in human tumor cells

Por Theys, Jan, Jutten, Barry, Habets, Roger, Paesmans, Kim, Groot, Arjan J., Lambin, Philippe, Wouters, Brad G., Lammering, Guido, Vooijs, Marc
Publicado no Radiother Oncol (2011)

Complete Genome Sequence of the Nonpathogenic Soil-Dwelling Bacterium Clostridium sporogenes Strain NCIMB 10696

Por Kubiak, Aleksandra M., Poehlein, Anja, Budd, Patrick, Kuehne, Sarah A., Winzer, Klaus, Theys, Jan, Lambin, Philip, Daniel, Rolf, Minton, Nigel P.
Publicado no Genome Announc (2015)

Advancing Clostridia to Clinical Trial: Past Lessons and Recent Progress

Por Mowday, Alexandra M., Guise, Christopher P., Ackerley, David F., Minton, Nigel P., Lambin, Philippe, Dubois, Ludwig J., Theys, Jan, Smaill, Jeff B., Patterson, Adam V.
Publicado no Cancers (Basel) (2016)

Spores of Clostridium engineered for clinical efficacy and safety cause regression and cure of tumors in vivo

Por Heap, John T., Theys, Jan, Ehsaan, Muhammad, Kubiak, Aleksandra M, Dubois, Ludwig, Paesmans, Kim, Van Mellaert, Lieve, Knox, Richard, Kuehne, Sarah A., Lambin, Phillipe, Minton, Nigel P.
Publicado em 2014

High NOTCH activity induces radiation resistance in non small cell lung cancer

Por Theys, Jan, Yahyanejad, Sanaz, Habets, Roger, Span, Paul, Dubois, Ludwig, Paesmans, Kim, Kattenbeld, Bo, Cleutjens, Jack, Groot, Arjan J., Schuurbiers, Olga C.J., Lambin, Philippe, Bussink, Jan, Vooijs, Marc
Publicado no Radiother Oncol (2013)

Myeloid DLL4 Does Not Contribute to the Pathogenesis of Non-Alcoholic Steatohepatitis in Ldlr(-/-) Mice

Por Jeurissen, Mike L. J., Walenbergh, Sofie M. A., Houben, Tom, Hendrikx, Tim, Li, Jieyi, Oligschlaeger, Yvonne, van Gorp, Patrick J., Gijbels, Marion J. J., Bitorina, Albert, Nessel, Isabell, Radtke, Freddy, Vooijs, Marc, Theys, Jan, Shiri-Sverdlov, Ronit
Publicado no PLoS One (2016)

NOTCH blockade combined with radiation therapy and temozolomide prolongs survival of orthotopic glioblastoma

Por Yahyanejad, Sanaz, King, Henry, Iglesias, Venus Sosa, Granton, Patrick V., Barbeau, Lydie M.O., van Hoof, Stefan J., Groot, Arjan J., Habets, Roger, Prickaerts, Jos, Chalmers, Anthony J., Eekers, Daniëlle B.P., Theys, Jan, Short, Susan C., Verhaegen, Frank, Vooijs, Marc
Publicado no Oncotarget (2016)