Lysine 63-Polyubiquitination Guards against Translesion Synthesis–Induced Mutations

Eukaryotic cells possess several mechanisms to protect the integrity of their DNA against damage. These include cell-cycle checkpoints, DNA-repair pathways, and also a distinct DNA damage–tolerance system that allows recovery of replication forks blocked at sites of DNA damage. In both humans and ye...

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Detalhes bibliográficos
Main Authors: Chiu, Roland K, Brun, Jan, Ramaekers, Chantal, Theys, Jan, Weng, Lin, Lambin, Philippe, Gray, Douglas A, Wouters, Bradly G
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1513265/
https://ncbi.nlm.nih.gov/pubmed/16789823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0020116
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