Lysine 63-linked polyubiquitination is required for EGF receptor degradation

Ubiquitination mediates endocytosis and endosomal sorting of various signaling receptors, transporters, and channels. However, the relative importance of mono- versus polyubiquitination and the role of specific types of polyubiquitin linkages in endocytic trafficking remain controversial. We used ma...

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Autors principals: Huang, Fangtian, Zeng, Xuemei, Kim, Woong, Balasubramani, Manimalha, Fortian, Arola, Gygi, Steven P., Yates, Nathan A., Sorkin, Alexander
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785728/
https://ncbi.nlm.nih.gov/pubmed/24019463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308014110
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