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Lysine 63-linked polyubiquitination is required for EGF receptor degradation
Ubiquitination mediates endocytosis and endosomal sorting of various signaling receptors, transporters, and channels. However, the relative importance of mono- versus polyubiquitination and the role of specific types of polyubiquitin linkages in endocytic trafficking remain controversial. We used ma...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3785728/ https://ncbi.nlm.nih.gov/pubmed/24019463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308014110 |
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