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Lysine-63-linked ubiquitination is required for endolysosomal degradation of class I molecules

MHC class I molecules display peptides from endogenous and viral proteins for immunosurveillance by cytotoxic T lymphocytes (CTL). The importance of the class I pathway is emphasised by the remarkable strategies employed by different viruses to downregulate surface class I and avoid CTL recognition....

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Bibliografske podrobnosti
Main Authors: Duncan, Lidia M, Piper, Siân, Dodd, Roger B, Saville, Mark K, Sanderson, Chris M, Luzio, J Paul, Lehner, Paul J
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440841/
https://ncbi.nlm.nih.gov/pubmed/16601694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601056
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