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Lysine-63-linked ubiquitination is required for endolysosomal degradation of class I molecules
MHC class I molecules display peptides from endogenous and viral proteins for immunosurveillance by cytotoxic T lymphocytes (CTL). The importance of the class I pathway is emphasised by the remarkable strategies employed by different viruses to downregulate surface class I and avoid CTL recognition....
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| Asıl Yazarlar: | , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2006
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1440841/ https://ncbi.nlm.nih.gov/pubmed/16601694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601056 |
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