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Lysine 63-linked Polyubiquitination Is Dispensable for Parkin-mediated Mitophagy

PINK1/Parkin-mediated mitophagy is thought to ensure mitochondrial quality control in neurons as well as other cells. Upon the loss of mitochondrial membrane potential (ΔΨm), Lys-63-linked polyubiquitin chains accumulate on the mitochondrial outer membrane in a Parkin-dependent manner. However, the...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Biol Chem
मुख्य लेखकों: Shiba-Fukushima, Kahori, Inoshita, Tsuyoshi, Hattori, Nobutaka, Imai, Yuzuru
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Biochemistry and Molecular Biology 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246074/
https://ncbi.nlm.nih.gov/pubmed/25336644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C114.580944
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