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PINK1-Mediated Phosphorylation of Parkin Boosts Parkin Activity in Drosophila
Two genes linked to early onset Parkinson's disease, PINK1 and Parkin, encode a protein kinase and a ubiquitin-ligase, respectively. Both enzymes have been suggested to support mitochondrial quality control. We have reported that Parkin is phosphorylated at Ser65 within the ubiquitin-like domai...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4046931/ https://ncbi.nlm.nih.gov/pubmed/24901221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004391 |
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