Reduced TDP-43 Expression Improves Neuronal Activities in a Drosophila Model of Perry Syndrome

Parkinsonian Perry syndrome, involving mutations in the dynein motor component dynactin or p150(Glued), is characterized by TDP-43 pathology in affected brain regions, including the substantia nigra. However, the molecular relationship between p150(Glued) and TDP-43 is largely unknown. Here, we repo...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Hosaka, Yuka, Inoshita, Tsuyoshi, Shiba-Fukushima, Kahori, Cui, Changxu, Arano, Taku, Imai, Yuzuru, Hattori, Nobutaka
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514405/
https://ncbi.nlm.nih.gov/pubmed/28625517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.06.002
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