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Light-driven activation of mitochondrial proton-motive force improves motor behaviors in a Drosophila model of Parkinson’s disease

Mitochondrial degeneration is considered one of the major causes of Parkinson’s disease (PD). Improved mitochondrial functions are expected to be a promising therapeutic strategy for PD. In this study, we introduced a light-driven proton transporter, Delta-rhodopsin (dR), to Drosophila mitochondria,...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Imai, Yuzuru, Inoshita, Tsuyoshi, Meng, Hongrui, Shiba-Fukushima, Kahori, Hara, Kiyotaka Y., Sawamura, Naoya, Hattori, Nobutaka
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6874642/
https://ncbi.nlm.nih.gov/pubmed/31799427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0674-1
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