hMMS2 serves a redundant role in human PCNA polyubiquitination

BACKGROUND: In yeast, DNA damage leads to the mono and polyubiquitination of the sliding clamp PCNA. Monoubiquitination of PCNA is controlled by RAD18 (E3 ligase) and RAD6 (E2 conjugating enzyme), while the extension of the monoubiquitinated PCNA into a polyubiquitinated substrate is governed by RAD...

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Bibliografiske detaljer
Main Authors: Brun, Jan, Chiu, Roland, Lockhart, Katherine, Xiao, Wei, Wouters, Bradly G, Gray, Douglas A
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2263069/
https://ncbi.nlm.nih.gov/pubmed/18284681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-9-24
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