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hMMS2 serves a redundant role in human PCNA polyubiquitination
BACKGROUND: In yeast, DNA damage leads to the mono and polyubiquitination of the sliding clamp PCNA. Monoubiquitination of PCNA is controlled by RAD18 (E3 ligase) and RAD6 (E2 conjugating enzyme), while the extension of the monoubiquitinated PCNA into a polyubiquitinated substrate is governed by RAD...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2263069/ https://ncbi.nlm.nih.gov/pubmed/18284681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-9-24 |
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