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E-Cadherin loss associated with EMT promotes radioresistance in human tumor cells

BACKGROUND AND PURPOSE: Hypoxia is a hallmark of solid cancers and associated with metastases and treatment failure. During tumor progression epithelial cells often acquire mesenchymal features, a phenomenon known as epithelial-to-mesenchymal transition (EMT). Intratumoral hypoxia has been linked to...

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Detalhes bibliográficos
Publicado no:Radiother Oncol
Main Authors: Theys, Jan, Jutten, Barry, Habets, Roger, Paesmans, Kim, Groot, Arjan J., Lambin, Philippe, Wouters, Brad G., Lammering, Guido, Vooijs, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948667/
https://ncbi.nlm.nih.gov/pubmed/21680037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.radonc.2011.05.044
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