Decreased 5-Hydroxymethylcytosine Is Associated with Neural Progenitor Phenotype in Normal Brain and Shorter Survival in Malignant Glioma

Epigenetic modification of DNA by cytosine methylation to produce 5-methylcytosine (5mC) has become well-recognized as an important epigenetic process in human health and disease. Recently, further modification of 5mC by the ten eleven translocated (TET) family of enzymes to produce 5-hydroxymethylc...

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Main Authors: Orr, Brent A., Haffner, Michael C., Nelson, William G., Yegnasubramanian, Srinivasan, Eberhart, Charles G.
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2012
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400598/
https://ncbi.nlm.nih.gov/pubmed/22829908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041036
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