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Tight correlation of 5-hydroxymethylcytosine and Polycomb marks in health and disease
Modifications to DNA and histone tails represent key epigenetic marks involved in establishing and maintaining cell identity and can be dysregulated in human diseases, including cancer. Two such modifications, tri-methylation of lysine-27 on histone H3 (H3K27me3) mediated by the Polycomb complex and...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3735697/ https://ncbi.nlm.nih.gov/pubmed/23676216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.25010 |
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