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Combination of methylated-DNA precipitation and methylation-sensitive restriction enzymes (COMPARE-MS) for the rapid, sensitive and quantitative detection of DNA methylation

Hypermethylation of CpG island (CGI) sequences is a nearly universal somatic genome alteration in cancer. Rapid and sensitive detection of DNA hypermethylation would aid in cancer diagnosis and risk stratification. We present a novel technique, called COMPARE-MS, that can rapidly and quantitatively...

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Hlavní autoři: Yegnasubramanian, Srinivasan, Lin, Xiaohui, Haffner, Michael C., DeMarzo, Angelo M., Nelson, William G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1363782/
https://ncbi.nlm.nih.gov/pubmed/16473842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnj022
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