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DNA methylation estimation using methylation-sensitive restriction enzyme bisulfite sequencing (MREBS)

Whole-genome bisulfite sequencing (WGBS) and reduced representation bisulfite sequencing (RRBS) are widely used for measuring DNA methylation levels on a genome-wide scale. Both methods have limitations: WGBS is expensive and prohibitive for most large-scale projects; RRBS only interrogates 6–12% of...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Bonora, Giancarlo, Rubbi, Liudmilla, Morselli, Marco, Ma, Feiyang, Chronis, Constantinos, Plath, Kathrin, Pellegrini, Matteo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6448829/
https://ncbi.nlm.nih.gov/pubmed/30946758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0214368
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