Quantification of DNA methylation independent of sodium bisulfite conversion using methylation‐sensitive restriction enzymes and digital PCR

Epigenetic regulation is important in human health and disease, but the exact mechanisms remain largely enigmatic. DNA methylation represents one epigenetic aspect but is challenging to quantify. In this study, we introduce a digital approach for the quantification of the amount and density of DNA m...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Hum Mutat
Egile Nagusiak: Nell, Rogier J., van Steenderen, Debby, Menger, Nino V., Weitering, Thomas J., Versluis, Mieke, van der Velden, Pieter A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2020
Gaiak:
Methods
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7756443/
https://ncbi.nlm.nih.gov/pubmed/32906203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.24111
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