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Tight correlation of 5-hydroxymethylcytosine and Polycomb marks in health and disease

Modifications to DNA and histone tails represent key epigenetic marks involved in establishing and maintaining cell identity and can be dysregulated in human diseases, including cancer. Two such modifications, tri-methylation of lysine-27 on histone H3 (H3K27me3) mediated by the Polycomb complex and...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Haffner, Michael C., Pellakuru, Laxmi G., Ghosh, Susmita, Lotan, Tamara L., Nelson, William G., De Marzo, Angelo M., Yegnasubramanian, Srinivasan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Landes Bioscience 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735697/
https://ncbi.nlm.nih.gov/pubmed/23676216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.25010
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