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Oncogenic KRAS promotes malignant brain tumors in zebrafish

BACKGROUND: Zebrafish have been used as a vertebrate model to study human cancers such as melanoma, rhabdomyosarcoma, liver cancer, and leukemia as well as for high-throughput screening of small molecules of therapeutic value. However, they are just emerging as a model for human brain tumors, which...

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Publicado en:Mol Cancer
Autores principales: Ju, Bensheng, Chen, Wenbiao, Orr, Brent A, Spitsbergen, Jan M, Jia, Sujuan, Eden, Christopher J, Henson, Hannah E, Taylor, Michael R
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4320811/
https://ncbi.nlm.nih.gov/pubmed/25644510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0288-2
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