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Development of a conditional liver tumor model by mifepristone-inducible Cre recombination to control oncogenic kras(V12) expression in transgenic zebrafish
Here we report a new transgenic expression system by combination of liver-specific expression, mifepristone induction and Cre-loxP recombination to conditionally control the expression of oncogenic kras(V12). This transgenic system allowed expression of kras(V12) specifically in the liver by a brief...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4726387/ https://ncbi.nlm.nih.gov/pubmed/26790949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19559 |
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