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Males develop faster and more severe hepatocellular carcinoma than females in kras(V12) transgenic zebrafish

Hepatocellular carcinoma (HCC) is more prevalent in men than women, but the reason for this gender disparity is not well understood. To investigate whether zebrafish could be used to study the gender disparity of HCC, we compared the difference of liver tumorigenesis between female and male fish dur...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Li, Yan, Li, Hankun, Spitsbergen, Jan M., Gong, Zhiyuan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5259773/
https://ncbi.nlm.nih.gov/pubmed/28117409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41280
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