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Males develop faster and more severe hepatocellular carcinoma than females in kras(V12) transgenic zebrafish

Hepatocellular carcinoma (HCC) is more prevalent in men than women, but the reason for this gender disparity is not well understood. To investigate whether zebrafish could be used to study the gender disparity of HCC, we compared the difference of liver tumorigenesis between female and male fish dur...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Li, Yan, Li, Hankun, Spitsbergen, Jan M., Gong, Zhiyuan
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5259773/
https://ncbi.nlm.nih.gov/pubmed/28117409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41280
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