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Males develop faster and more severe hepatocellular carcinoma than females in kras(V12) transgenic zebrafish

Hepatocellular carcinoma (HCC) is more prevalent in men than women, but the reason for this gender disparity is not well understood. To investigate whether zebrafish could be used to study the gender disparity of HCC, we compared the difference of liver tumorigenesis between female and male fish dur...

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Publicat a:Sci Rep
Autors principals: Li, Yan, Li, Hankun, Spitsbergen, Jan M., Gong, Zhiyuan
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5259773/
https://ncbi.nlm.nih.gov/pubmed/28117409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41280
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