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Synergistic Induction of Potential Warburg Effect in Zebrafish Hepatocellular Carcinoma by Co-Transgenic Expression of Myc and xmrk Oncogenes

Previously we have generated inducible liver tumor models by transgenic expression of Myc or xmrk (activated EGFR homolog) oncogenes in zebrafish. To investigate the interaction of the two oncogenes, we crossed the two transgenic lines and observed more severe and faster hepatocarcinogenesis in Myc/...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Li, Zhen, Zheng, Weiling, Li, Hankun, Li, Caixia, Gong, Zhiyuan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492623/
https://ncbi.nlm.nih.gov/pubmed/26147004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132319
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