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Xmrk, Kras and Myc Transgenic Zebrafish Liver Cancer Models Share Molecular Signatures with Subsets of Human Hepatocellular Carcinoma

Previously three oncogene transgenic zebrafish lines with inducible expression of xmrk, kras or Myc in the liver have been generated and these transgenic lines develop oncogene-addicted liver tumors upon chemical induction. In the current study, comparative transcriptomic approaches were used to exa...

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Main Authors: Zheng, Weiling, Li, Zhen, Nguyen, Anh Tuan, Li, Caixia, Emelyanov, Alexander, Gong, Zhiyuan
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954698/
https://ncbi.nlm.nih.gov/pubmed/24633177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091179
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