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Myc-Induced Liver Tumors in Transgenic Zebrafish Can Regress in tp53 Null Mutation

Hepatocellular carcinoma (HCC) is currently one of the top lethal cancers with an increasing trend. Deregulation of MYC in HCC is frequently detected and always correlated with poor prognosis. As the zebrafish genome contains two differentially expressed zebrafish myc orthologs, myca and mycb, it re...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sun, Lili, Nguyen, Anh Tuan, Spitsbergen, Jan M., Gong, Zhiyuan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303426/
https://ncbi.nlm.nih.gov/pubmed/25612309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117249
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