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Myc-Induced Liver Tumors in Transgenic Zebrafish Can Regress in tp53 Null Mutation
Hepatocellular carcinoma (HCC) is currently one of the top lethal cancers with an increasing trend. Deregulation of MYC in HCC is frequently detected and always correlated with poor prognosis. As the zebrafish genome contains two differentially expressed zebrafish myc orthologs, myca and mycb, it re...
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Publicado no: | PLoS One |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4303426/ https://ncbi.nlm.nih.gov/pubmed/25612309 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117249 |
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