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Myc-Induced Liver Tumors in Transgenic Zebrafish Can Regress in tp53 Null Mutation

Hepatocellular carcinoma (HCC) is currently one of the top lethal cancers with an increasing trend. Deregulation of MYC in HCC is frequently detected and always correlated with poor prognosis. As the zebrafish genome contains two differentially expressed zebrafish myc orthologs, myca and mycb, it re...

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Sun, Lili, Nguyen, Anh Tuan, Spitsbergen, Jan M., Gong, Zhiyuan
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303426/
https://ncbi.nlm.nih.gov/pubmed/25612309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117249
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