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Myc-Induced Liver Tumors in Transgenic Zebrafish Can Regress in tp53 Null Mutation
Hepatocellular carcinoma (HCC) is currently one of the top lethal cancers with an increasing trend. Deregulation of MYC in HCC is frequently detected and always correlated with poor prognosis. As the zebrafish genome contains two differentially expressed zebrafish myc orthologs, myca and mycb, it re...
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| Опубликовано в: : | PLoS One |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4303426/ https://ncbi.nlm.nih.gov/pubmed/25612309 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117249 |
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