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Myc-Induced Liver Tumors in Transgenic Zebrafish Can Regress in tp53 Null Mutation

Hepatocellular carcinoma (HCC) is currently one of the top lethal cancers with an increasing trend. Deregulation of MYC in HCC is frequently detected and always correlated with poor prognosis. As the zebrafish genome contains two differentially expressed zebrafish myc orthologs, myca and mycb, it re...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Sun, Lili, Nguyen, Anh Tuan, Spitsbergen, Jan M., Gong, Zhiyuan
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303426/
https://ncbi.nlm.nih.gov/pubmed/25612309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117249
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