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Activation of liver stromal cells is associated with male-biased liver tumor initiation in xmrk and Myc transgenic zebrafish

Hepatocellular carcinoma (HCC) is more prevalent in men than in women. Previously we have found that some stromal cells, including hepatic stellate cells (HSCs), neutrophils and macrophages, play crucial roles in promoting sex disparity in kras (V12)-induced zebrafish HCC. The activation of HSCs is...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Yang, Qiqi, Yan, Chuan, Gong, Zhiyuan
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5583234/
https://ncbi.nlm.nih.gov/pubmed/28871112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10529-1
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