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Interaction of hepatic stellate cells with neutrophils and macrophages in the liver following oncogenic kras activation in transgenic zebrafish

Activation of hepatic stellate cells (HSC) plays a crucial role in the liver disease progression from liver fibrosis/cirrhosis to cancer. Here, we found a rapid change of microenvironment after kras(V12)-induction in zebrafish liver with progressively increased stromal cell number and enlarged liver...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Yang, Qiqi, Yan, Chuan, Gong, Zhiyuan
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5981472/
https://ncbi.nlm.nih.gov/pubmed/29855567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26612-0
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