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Oncogenic KRAS induces progenitor cell expansion and malignant transformation in zebrafish exocrine pancreas
BACKGROUND AND AIMS: Although the cell of origin for pancreatic cancer remains unknown, prior studies have suggested that pancreatic neoplasia may be initiated in progenitor-like cells. In order to examine the effects of oncogene activation within the pancreatic progenitor pool, we devised a system...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2654247/ https://ncbi.nlm.nih.gov/pubmed/18549880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2008.02.084 |
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