Prox1-Heterozygosis Sensitizes the Pancreas to Oncogenic Kras-Induced Neoplastic Transformation()()

The current paradigm of pancreatic neoplastic transformation proposes an initial step whereby acinar cells convert into acinar-to-ductal metaplasias, followed by progression of these lesions into neoplasias under sustained oncogenic activity and inflammation. Understanding the molecular mechanisms d...

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Vydáno v:Neoplasia
Hlavní autoři: Drosos, Yiannis, Neale, Geoffrey, Ye, Jianming, Paul, Leena, Kuliyev, Emin, Maitra, Anirban, Means, Anna L, Washington, M Kay, Rehg, Jerold, Finkelstein, David B, Sosa-Pineda, Beatriz
Médium: Artigo
Jazyk:Inglês
Vydáno: Neoplasia Press 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4796801/
https://ncbi.nlm.nih.gov/pubmed/26992918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2016.02.002
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