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Nature versus Nurture in Glioblastoma: Microenvironment and Genetics Can Both Drive Mesenchymal Transcriptional Signature

This Commentary highlights the article by Cooper et al, which describes the association of mesenchymal glioblastoma with necrosis and poor prognosis, suggesting key signaling nodes for targeted therapies.

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Detalhes bibliográficos
Main Authors: Orr, Brent A., Eberhart, Charles G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349836/
https://ncbi.nlm.nih.gov/pubmed/22449951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.03.001
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