Pyruvate and Metabolic Flexibility: Illuminating a path toward selective cancer therapies

Por Olson, Kristofor A., Schell, John C., Rutter, Jared
Publicado no Trends Biochem Sci (2016)

A role for the mitochondrial pyruvate carrier as a repressor of the Warburg Effect and colon cancer cell growth

Por Schell, John C., Olson, Kristofor A., Jiang, Lei, Hawkins, Amy J., Van Vranken, Jonathan G., Xie, Jianxin, Egnatchik, Robert A., Earl, Espen G., Deberardinis, Ralph J., Rutter, Jared
Publicado no Mol Cell (2014)

A metabolic switch controls intestinal differentiation downstream of Adenomatous polyposis coli (APC)

Por Sandoval, Imelda T, Delacruz, Richard Glenn C, Miller, Braden N, Hill, Shauna, Olson, Kristofor A, Gabriel, Ana E, Boyd, Kevin, Satterfield, Christeena, Van Remmen, Holly, Rutter, Jared, Jones, David A
Publicado no eLife (2017)

Control of intestinal stem cell function and proliferation by mitochondrial pyruvate metabolism

Por Schell, John C., Wisidagama, Dona R., Bensard, Claire, Zhao, Helong, Wei, Peng, Tanner, Jason, Flores, Aimee, Mohlman, Jeffrey, Sorensen, Lise K., Earl, Christian S., Olson, Kristofor A., Miao, Ren, Waller, T. Cameron, Delker, Don, Kanth, Priyanka, Jiang, Lei, DeBerardinis, Ralph J., Bronner, Mary P., Li, Dean Y., Cox, James E., Christofk, Heather R., Lowry, William E., Thummel, Carl S., Rutter, Jared
Publicado no Nat Cell Biol (2017)