A metabolic switch controls intestinal differentiation downstream of Adenomatous polyposis coli (APC)

Elucidating signaling pathways that regulate cellular metabolism is essential for a better understanding of normal development and tumorigenesis. Recent studies have shown that mitochondrial pyruvate carrier 1 (MPC1), a crucial player in pyruvate metabolism, is downregulated in colon adenocarcinomas...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Sandoval, Imelda T, Delacruz, Richard Glenn C, Miller, Braden N, Hill, Shauna, Olson, Kristofor A, Gabriel, Ana E, Boyd, Kevin, Satterfield, Christeena, Van Remmen, Holly, Rutter, Jared, Jones, David A
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Cancer Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5388534/
https://ncbi.nlm.nih.gov/pubmed/28397687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.22706
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