Introduction to NIRS International Open Laboratory (IOL)

Por Okayasu, Ryuichi
Publicado em 2014

TAS-116, a novel Hsp90 inhibitor, selectively enhances radio-sensitivity of human cancer cells to X-rays and carbon ion radiation

Por Lee, Younghyun, Sunada, Shigeaki, Hirakawa, Hirokazu, Fujimori, Akira, Nickoloff, Jac A., Okayasu, Ryuichi
Publicado no Mol Cancer Ther (2016)

Role of the Nfo and ExoA Apurinic/Apyrimidinic Endonucleases in Radiation Resistance and Radiation-Induced Mutagenesis of Bacillus subtilis Spores

Por Moeller, Ralf, Setlow, Peter, Pedraza-Reyes, Mario, Okayasu, Ryuichi, Reitz, Günther, Nicholson, Wayne L.
Publicado em 2011

DNA double-strand break induction in Ku80-deficient CHO cells following Boron Neutron Capture Reaction

Por Kinashi, Yuko, Takahashi, Sentaro, Kashino, Genro, Okayasu, Ryuichi, Masunaga, Shinichiro, Suzuki, Minoru, Ono, Koji
Publicado em 2011

Relative biological effects of neutron mixed-beam irradiation for boron neutron capture therapy on cell survival and DNA double-strand breaks in cultured mammalian cells

Por Okumura, Kakuji, Kinashi, Yuko, Kubota, Yoshihisa, Kitajima, Erika, Okayasu, Ryuichi, Ono, Koji, Takahashi, Sentaro
Publicado em 2013

In vitro characterization of cells derived from chordoma cell line U-CH1 following treatment with X-rays, heavy ions and chemotherapeutic drugs

Por Kato, Takamitsu A, Tsuda, Akihisa, Uesaka, Mitsuru, Fujimori, Akira, Kamada, Tadashi, Tsujii, Hirohiko, Okayasu, Ryuichi
Publicado em 2011

Pre-Exposure to Ionizing Radiation Stimulates DNA Double Strand Break End Resection, Promoting the Use of Homologous Recombination Repair

Por Nakajima, Nakako Izumi, Hagiwara, Yoshihiko, Oike, Takahiro, Okayasu, Ryuichi, Murakami, Takeshi, Nakano, Takashi, Shibata, Atsushi
Publicado no PLoS One (2015)

Hsp90 inhibitor is a good candidate for effective combination therapy with carbon ions

Por Okayasu, Ryuichi, Hirakawa, Hirokazu, Masaoka, Aya, Noguchi, Miho, Hirayama, Ryoichi, Li, Huizi, Matsumoto, Yoshitaka, Fujimori, Akira
Publicado em 2014

The combination of Hsp90 inhibitor 17AAG and heavy-ion irradiation provides effective tumor control in human lung cancer cells

Por Hirakawa, Hirokazu, Fujisawa, Hiroshi, Masaoka, Aya, Noguchi, Miho, Hirayama, Ryoichi, Takahashi, Momoko, Fujimori, Akira, Okayasu, Ryuichi
Publicado no Cancer Med (2015)

Resistance of Bacillus subtilis Spore DNA to Lethal Ionizing Radiation Damage Relies Primarily on Spore Core Components and DNA Repair, with Minor Effects of Oxygen Radical Detoxif...

Por Moeller, Ralf, Raguse, Marina, Reitz, Günther, Okayasu, Ryuichi, Li, Zuofeng, Klein, Stuart, Setlow, Peter, Nicholson, Wayne L.
Publicado em 2014

The purine scaffold Hsp90 inhibitor PU-H71 sensitizes cancer cells to heavy ion radiation by inhibiting DNA repair by homologous recombination and non-homologous end joining

Por Lee, Younghyun, Li, Huizi, Masaoka, Aya, Sunada, Shigeaki, Hirakawa, Hirokazu, Fujimori, Akira, Nickoloff, Jac A., Okayasu, Ryuichi
Publicado no Radiother Oncol (2016)

A comprehensive analysis of radiosensitization targets; functional inhibition of DNA methyltransferase 3B radiosensitizes by disrupting DNA damage regulation

Por Fujimori, Hiroaki, Sato, Akira, Kikuhara, Sota, Wang, Junhui, Hirai, Takahisa, Sasaki, Yuka, Murakami, Yasufumi, Okayasu, Ryuichi, Masutani, Mitsuko
Publicado no Sci Rep (2015)

Nontoxic concentration of DNA‐PK inhibitor NU7441 radio‐sensitizes lung tumor cells with little effect on double strand break repair

Por Sunada, Shigeaki, Kanai, Hideki, Lee, Younghyun, Yasuda, Takeshi, Hirakawa, Hirokazu, Liu, Cuihua, Fujimori, Akira, Uesaka, Mitsuru, Okayasu, Ryuichi
Publicado no Cancer Sci (2016)

VE-821, an ATR inhibitor, causes radiosensitization in human tumor cells irradiated with high LET radiation

Por Fujisawa, Hiroshi, Nakajima, Nakako Izumi, Sunada, Shigeaki, Lee, Younghyun, Hirakawa, Hirokazu, Yajima, Hirohiko, Fujimori, Akira, Uesaka, Mitsuru, Okayasu, Ryuichi
Publicado no Radiat Oncol (2015)

Roles of the Major, Small, Acid-Soluble Spore Proteins and Spore-Specific and Universal DNA Repair Mechanisms in Resistance of Bacillus subtilis Spores to Ionizing Radiation from X...

Por Moeller, Ralf, Setlow, Peter, Horneck, Gerda, Berger, Thomas, Reitz, Günther, Rettberg, Petra, Doherty, Aidan J., Okayasu, Ryuichi, Nicholson, Wayne L.
Publicado em 2008

Visualisation of γH2AX Foci Caused by Heavy Ion Particle Traversal; Distinction between Core Track versus Non-Track Damage

Por Nakajima, Nakako Izumi, Brunton, Holly, Watanabe, Ritsuko, Shrikhande, Amruta, Hirayama, Ryoichi, Matsufuji, Naruhiro, Fujimori, Akira, Murakami, Takeshi, Okayasu, Ryuichi, Jeggo, Penny, Shibata, Atsushi
Publicado em 2013

Selective Enhancing Effect of Early Mitotic Inhibitor 1 (Emi1) Depletion on the Sensitivity of Doxorubicin or X-ray Treatment in Human Cancer Cells

Por Shimizu, Natsumi, Nakajima, Nakako Izumi, Tsunematsu, Takaaki, Ogawa, Ikuko, Kawai, Hidehiko, Hirayama, Ryoichi, Fujimori, Akira, Yamada, Akiko, Okayasu, Ryuichi, Ishimaru, Naozumi, Takata, Takashi, Kudo, Yasusei
Publicado em 2013

DNA Damage Response Proteins and Oxygen Modulate Prostaglandin E(2) Growth Factor Release in Response to Low and High LET Ionizing Radiation

Por Allen, Christopher P., Tinganelli, Walter, Sharma, Neelam, Nie, Jingyi, Sicard, Cory, Natale, Francesco, King, Maurice, Keysar, Steven B., Jimeno, Antonio, Furusawa, Yoshiya, Okayasu, Ryuichi, Fujimori, Akira, Durante, Marco, Nickoloff, Jac A.
Publicado no Front Oncol (2015)