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Pre-Exposure to Ionizing Radiation Stimulates DNA Double Strand Break End Resection, Promoting the Use of Homologous Recombination Repair

The choice of DNA double strand break (DSB) repair pathway is determined at the stage of DSB end resection. Resection was proposed to control the balance between the two major DSB repair pathways, homologous recombination (HR) and non-homologous end joining (NHEJ). Here, we examined the regulation o...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Nakajima, Nakako Izumi, Hagiwara, Yoshihiko, Oike, Takahiro, Okayasu, Ryuichi, Murakami, Takeshi, Nakano, Takashi, Shibata, Atsushi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380452/
https://ncbi.nlm.nih.gov/pubmed/25826455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122582
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